CSS is simple, isn't it? Then try this: I was looking to implement an application design which uses the full screen (regardless of end user's view port resolution) and has a simple 3 or 2 column layout. It has a header section, no footer, but the tricky part was that the columns have to fill down the whole lenght of the browser.
I needed three attempts and I read a whole CSS book (Fexible Web Design - Creating Liquid and Elastic Layouts with CSS) in between to get where I am today. You can download my example or you can try it yourself.